|
KMID : 0032220110230010119
|
|
Annals of Dermatology
2011 Volume.23 No. 1 p.119 ~ p.122
|
|
|
Sorafenib (Nexavarⓡ, BAY 43-9006)-induced Hand-foot Skin Reaction with Facial Erythema
|
|
Kim Dong-Ha
Son In-Pyeong
Lee Jin-Woong
Lee Hye-In
Kim Beom-Joon
Kim Myeung-Nam
|
|
|
Abstract
|
|
|
|
Sorafenib (Nexavarⓡ, BAY 43-9006) is a novel, orally administered multi-kinase inhibitor that has recently been approved for the treatment of metastatic renal cell carcinoma. It is also used to delay disease progression in patients with advanced solid organ malignancies and metastatic melanoma. Sorafenib is associated with a relatively high incidence of dermatologic adverse events. The commonly occurring dermatologic adverse events associated with sorafenib include hand-foot skin reaction, facial erythema, splinter subungual hemorrhages, alopecia, pruritus and xerosis. We report here on a case of a 50-year-old man who was diagnosed with metastatic hepatocellular carcinoma. He developed both facial erythema and hand-foot skin reaction after the administration of sorafenib
|
|
|
KEYWORD
|
|
|
Facial erythema, Hand-foot skin reaction, Sorafenib
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
   
|